25 JULY 2014 • VOLUME 345 • ISSUE 6195
CONTENTS
NEWS
IN BRIEF
362 Roundup of the week’s news
IN DEP TH
364 EBOLA DRUGS STILL STUCK IN LAB
Experts discussed—and rejected—
bringing experimental vaccines and
therapies to West Africa By M. Enserink
365 ROAD HAZARDS THREATEN ROVER
To limit wheel damage from sharp
rocks, the Curiosity Mars rover detours
into sandy valleys By E. Hand
366 NIH INSTITUTE CONSIDERS BROAD
SHIFT TO ‘PEOPLE’ AWARDS
Approach promises freedom from grant
writing but could favor established
researchers By J. Kaiser
▶ PODCAST
367 DENGUE VACCINE TRIAL POSES
PUBLIC HEALTH QUANDARY
Experimental vaccine fell short against
key strain By D. Normile
368 OIL SANDS FIGHT HEATS UP IN U.S.
Environmentalists oppose federal lease
in Utah By D. Malakoff
FEATURE
370 FUSION’S RESTLESS PIONEERS
Startups with novel technologies are
taking on fusion’s Goliaths By D. Clery
INSIGHTS
PERSPECTIVES
376 WILDLIFE DECLINE AND
SOCIAL CONFLICT
Policies aimed at reducing wildlife-
related conflict must address the
underlying causes By J. S. Brashares et al.
▶ VANISHING FAUNA SEC TION P. 392
378 RIBOSOME RESCUE AND
NEURODEGENERATION
A mutation in a brain-specific tRNA
reveals the link between ribosome
maintenance and neuronal cell death
By J. C. Darnell
▶ REPORT P. 455
380 ULTRASLOW RELAXATION
OF CONFINED DNA
DNA dynamics in tight spaces challenge
nature’s nanomachines By Y. R. Chemla
and T. Ha
381 SELF-CONTROL TAMES THE
COUPLING OF REACTIVE RADICALS
Iridium complexes use two points
of contact to control carbon-carbon
bond formation By G. C. Lloyd-Jones
and L. T. Ball
▶ REPORTS PP. 433 & 437
383 WHY ARE PLANT-POLLINATOR
NETWORKS NESTED?
Mutualistic communities maximize
their structural stability By S. Pawar
▶ RESEARCH ARTICLE P. 416
SPECIAL SECTION
Vanishing fauna
INTRODUCTION
392 Vanishing fauna
NEWS
396 The empty forest
By E. Stokstad
OPINION
400 An animal-rich future
By J. J. Tewksbury and H. S. Rogers
REVIEWS
401 Defaunation in the Anthropocene
R. Dirzo et al.
406 Reversing defaunation: Restoring
species in a changing world
P. J. Seddon et al.
392
ON THE COVER
A male clouded
leopard (Neofelis
diardi borneensis)
caught by a camera
trap in the lowland
rainforest of Borneo.
If the cataract in
his right eye indi-
cates old age, he
has been fortunate. Animals from rare
predators to common invertebrates are
experiencing a human-caused global
decline that often leads to extinction,
with consequences for ecosystems and
human well-being. See page 392. Photo:
© Sebastian Kennerknecht/Panthera
370
SEE ALSO ▶
sciencemag.org/special/vanishing ▶ PERSPECTIVE P. 376 ▶ BOOK REVIEW P. 388
384 & 427
Cloaking objects with
just the right coating