Copper’s ups and downs
353 & 385
We still need to beat HIV
By François Dabis and Linda-Gail Bekker
422 WORKING LIFE
From abalone to advocacy
By Alyssa R. Frederick
366 From Science and other journals
Kynurenines: Tryptophan’s metabolites
in exercise, inflammation, and mental
health I. Cervenka et al.
REVIEW SUMMARY; FOR FULL TEXT:
370 CHROMATIN STRUCTURE
ChromEMT: Visualizing 3D chromatin
structure and compaction in interphase
and mitotic cells H. D. Ou et al.
RESEARCH ARTICLE SUMMARY; FOR FULL TEXT:
▶ PERSPECTIVE P. 354
371 DNA NANOTECHNOLOGY
Reconfiguration of DNA molecular
arrays driven by information relay
J. Song et al.
RESEARCH ARTICLE SUMMARY; FOR FULL TEXT:
▶ PERSPECTIVE P. 352
372 ULTRACOLD MOLECULES
Second-scale nuclear spin coherence
time of ultracold 23Na40K molecules
J. W. Park et al.
375 X-RAY OPTICS
Spectral narrowing of x-ray pulses
for precision spectroscopy with nuclear
resonances K. P. Heeg et al.
Tough adhesives for diverse wet
surfaces J. Li et al.
382 HIGH-PRESSURE PHYSICS
Synthesis of FeH5: A layered structure
with atomic hydrogen slabs
C. M. Pépin et al.
Direct optical lithography of functional
inorganic nanomaterials Y. Wang et al.
▶ PERSPEC TIVE P. 353
Atomic-layered Au clusters on a-MoC
as catalysts for the low-temperature
water-gas shift reaction S. Yao et al.
Seismic evidence for partial melting at
the root of major hot spot plumes
K. Yuan and B. Romanowicz
Nanocrystalline copper films are never
flat X. Zhang et al.
Control of species-dependent cortico-motoneuronal connections underlying
manual dexterity Z. Gu et al.
405 NITROGEN POLLUTION
Eutrophication will increase during the
21st century as a result of precipitation
changes E. Sinha et al.
▶ PERSPECTIVE P. 350
409 CANCER BIOMARKERS
Mismatch repair deficiency predicts
response of solid tumors to PD-1
blockade D. T. Le et al.
▶ PERSPECTIVE P. 358
CAT-tailing as a fail-safe mechanism for
efficient degradation of stalled nascent
polypeptides K. K. Kostova et al.
ON THE COVER
of chromatin inside a
cell’s nucleus. To fit in
the nucleus and mitotic
chromosomes, DNA is
assembled into chro-
matin, the structure
of which determines
the functions of our
genome. By painting cells with a DNA bind-
ing dye that deposits a metal dusting on the
surface of DNA, Ou et al. were able to visu-
alize the chromatin structure of the human
genome. For more on the process behind
the cover image, see http://scim.ag/2tUczje.
Illustration: Valerie Altounian/Science
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364 CALL TO RESTORE NIH’S
CAP ON GRANT FUNDING
By M. Peifer