Cancer HotSpot Panel
Using a unique approach, the NEBNext Direct
Cancer HotSpot Panel enriches for 190 common
cancer targets from 50 genes prior to next generation
sequencing. Combining a novel method for
hybridization-based target enrichment with library
preparation, the NEBNext Direct technology reduces
processing time and minimizes sample loss. Ideal for
automation, NEBNext Direct enables highly-specific
deep sequencing of genomic regions of interest for the
discovery and identification of low frequency variants
from challenging sample types.
Visit NEBNextDirect.com to learn more
and to inquire about sampling this product.
TARGETS INCLUDE REGIONS FROM THE FOLLOWING
CANCER-RELATED GENES, INCLUDING >18,000
ABL1 EGFR GNAQ KRAS PTPN11
AKT1 ERBB2 GNAS MET RB1
ALK ERBB4 HNF1A MLH1 RET
APC EZH2 HRAS MPL SMAD4
ATM FBXW7 IDH1 NOTCH1 SMARCB1
BRAF FGFR1 IDH2 NPM1 SMO
CDH1 FGFR2 JAK2 NRAS SRC
CDKN2A FGFR3 JAK3 PDGFRA STK11
CSF1R FLT3 KDR PIK3CA TP53
CTNNB1 GNA11 KIT PTEN VHL
For research use only; not intended for diagnostic use.
NEW ENGLAND BIOLABS® and NEB® are registered trademarks of New England Biolabs, Inc.
NEBNEXT DIRECT™ is a trademark of New England Biolabs, Inc.