9 FEBRUARY 2018 • VOL 359 ISSUE 6376 609 SCIENCE sciencemag.org
Kinked b sheets
War and peace in the nuclear age
By E. William Colglazier
706 WORKING LIFE
My climate change crisis
By Paul C. Rogge
648 From Science and other journals
651 SYNTHETIC BIOLOGY
Programming gene and engineered-cell
therapies with synthetic biology
T. Kitada et al.
REVIEW SUMMARY; FOR FULL TEX T:
652 MOLECULAR BIOLOGY
A pathway for mitotic chromosome
formation J. H. Gibcus et al.
RESEARCH ARTICLE SUMMARY; FOR FULL TEX T:
Morphology, muscle capacity, skill, and
maneuvering ability in hummingbirds
R. Dakin et al.
▶ PERSPEC TIVE P. 636; VIDEO
Live imaging of neurogenesis in
the adult mouse hippocampus
G.-A. Pilz et al.
▶ PERSPEC TIVE P. 639
662 QUANTUM OPTICS
Coherent single-atom superradiance
J. Kim et al.
▶ PERSPEC TIVE P. 641
666 QUANTUM OPTICS
A topological quantum optics interface
S. Barik et al.
▶ PERSPEC TIVE P. 638
Building superlattices from
individual nanoparticles via template-
confined DNA-mediated assembly
Q.-Y. Lin et al.
Light amplification by seeded Kerr
instability G. Vampa et al.
675 MATERIALS SCIENCE
electron microscopy of electron
beam–sensitive crystalline materials
D. Zhang et al.
Near-infrared deep brain stimulation
via upconversion nanoparticle–
mediated optogenetics S. Chen et al.
▶ PERSPEC TIVE P. 633
684 TISSUE REGENERATION
Defective cholesterol clearance limits
remyelination in the aged central
L. Cantuti-Castelvetri et al.
▶ PERSPEC TIVE P. 635
689 PROTEIN TARGETING
Defining the physiological role of
SRP in protein-targeting efficiency
and specificity E. A. Costa et al.
693 PSYCHIATRIC GENOMICS
Shared molecular neuropathology
across major psychiatric disorders
parallels polygenic overlap
M. J. Gandal et al.
▶ NEWS STORY P. 619
698 PROTEIN BIOCHEMISTRY
Atomic structures of low-complexity
protein segments reveal kinked
b sheets that assemble networks
M. P. Hughes et al.
ON THE COVER
maneuvers in flight.
known for their
ability to rapidly
and turn on a dime. Species vary in aerial
maneuvering performance, and different
aspects of maneuverability evolve as a
result of various biomechanical traits. This
framework may apply to other organisms
and to the design of more maneuverable
aircraft. See pages 636 and 653.
Photo: Glenn Bartley/BIA/Minden Pictures
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BOOKS ET AL.
644 DATA RICH
If liberal democracies can resist the urge
to micromanage the economy, big data
could catalyze a new capitalism
By A. W. Lo
645 BE TTER TOGE THER
A pair of policy experts highlights
tension in team science and,
inadvertently, in the study of scientific
teams By S. M. Fiore
By M. Blicharska and R. J. Smithers
LOGGING DATA LACKING
By M. Konarzewski et al.
646 TRANSPORT EXPANSION
THREATENS THE ARC TIC
By H. Yang et al.